Dr Yang Li

CURRICULUM VITAE

Education and Experience

1.	Year:	Nov 2007 ~
	Practice:	BrightNow Dental Inc
	Position	Lead Dentist Market Dental Director (North LA area, 11 offices)
2.	Year:	May 2006 ~ Nov 2007
	Practice:	General Dentistry
	Offices:	Steve JH Lee Dental Office at West Los Angeles (part time, May 2006 to now) Western Dental Dental Services (part time, May 2006 to May 2007) Dan Rosen Dental Office at Encino (part time, March 2007 to October 2007)
3.	Year:	April, 2005 ~ September 2006
	School:	Urology, David Geffen School of Medicine, UCLA
	Position:	Assistant Researcher
	Projects:	Urosensor for Uropathogen Detection
4.	Year:	February, 2003 ~ March, 2005
	School:	School of Dentistry/Dental Research Institute, UCLA
	Position:	PostDoctoral Fellow and Assistant Researcher
	Projects:	Bodily-fluid based molecular diagnostics for human diseases (Diabetes II, Breast cancer, Oral premalignancy, et al) Oral Fluid MEMS/NEMS Chip for Head & Neck cancer detection Salivary Transcriptome Diagnostics for head & neck cancer early detection
5.	Year:	March, 2002 ~ November, 2005 (moved to USA at March 2002)
	Training:	Duggan Study Institute and UCLA School of Dentistry, for CA Dental Board License Exam (Passed CA Dental Board Exam and Received Liscence since November, 2005)
6.	Year:	July, 2001 ~ March 2002
	School:	School of Dentistry, Sichuan University, China
	Position:	Lecturer
7.	Year:	September, 1998 ~ June, 2001
	School:	Sichuan University, China
	Credential:	Doctor of Medical Science
	Degree:	US equivalent of a Doctor of Philosophy degree in Dentistry (* ECE)
8.	Year:	September, 1991~ September, 1998
	School:	West China University of Medical Sciences, China
	Credential:	Master of Medicine, confirming of a dentistry program in China
	Degree:	US equivalent of a Doctor of Dental Surgery degree (*ECE)

*ECE: Educational Credential Evaluators, Inc, Wisconsin, USA

Publications

St. John MAR, Li Y, Zhou XF, et al (2004). IL-6 and IL-8: potential biomarkers for oral cavity and oropharyngeal SCCA. Arch Otolaryngol Head Neck Surg 130:929-935.

Li Y, Zhou X, St. John MAR et al (2004). RNA Profiling of Cell-free Saliva Using Microarray Technology. J Dent Res 83(3): 199-203.

Li Y, St. John MAR, Zhou XF, et al (2004). Salivary Transcriptome Diagnostics for Oral Cancer Detection. Clin Can Res 10(24): 8442-50.

X. Zhou, S.C. Mok, Z. Chen, Y. Li and D.T. Wong (2004). Concurrent analysis of loss of heterozygosity (LOH) and copy number abnormality (CNA) for oral premalignancy progression using Affymetrix 10K SNP mapping array. Hum Genet 115(4): 327-302.

X. Zhou, S.W. Cole, N.P. Rao, Z. Chen, Y. Li, J. McBride, and D.T. Wong (2005). Identification of discrete chromosomal deletion by binary recursive partitioning of microarray differential expression data. J Med Genet 42(5):416-9..

X. Zhou, R.C.K. Jordan, Y. Li, B.L. Huang, and D.T. Wong (2005). Frequent allelic imbalance at 8p and 11q22 in oral cavity and oropharyngeal epithelial dysplastic lesions. Cancer Genet Cytogenet 161(1):86-9.

Shen Hu, Yongming Xie, Prasanna Ramachandran, Rachel R. Ogorzalek Loo, Yang Li, Joseph A. Loo, David Wong (2005). Large-scale identification of proteins in human salivary proteome by liquid chromatography/mass spectrometry and two-dimensional gel electrophoresis/mass spectrometry. Proteomics 5(6):1714-28.

Shen Hu, Patricia Denny, Paul Denny, Yongming Xie, Joseph A. Loo, Lawrence E. Wolinsky, Yang Li, Jim Mcbride, Rachel R. Ogorzalek Loo Mavash Navazesh and David T. Wong (2004). Differentially expressed proteins markers in human submandibular and sublingual secretions. Int J Oncol 25(5):1423-30.

Yang Li, Paul Denny, Chih-Ming Ho, Carlo Montemagno, Wenyuan Shi, Fengxia Qi, Benjamin Wu, Lawrence Wolinsky and David T. Wong (2005). The Oral Fluid MEMS/NEMS Chip (OFMNC): Diagnostic & Translational Applications. Adv Dent Res 18: 3-5.

Yang Li, David Elashoff, Myungshin Oh, Uttam Sinha, Maie A.R. St. John, Xiaofeng Zhou, Elliot Abemayor, and David T. Wong (2005). Serum Circulating Human mRNA Profiling and Its Utility for Oral Cancer Detection. J Clin Onco, 2006 Apr 10;24(11):1754-60.

Y Kim, Y Li, X. Zhou, et al. Combined Expression Microarray and Pathway Analysis to identify target genes. Can Res 2005

Shen Hu, Yang Li, et al. Salivary Proteome and Transcriptome. J Dent Res 2005

Hu S, Denny P, Denny P, Xie Y, Loo JA, Wolinsky LE, Li Y, McBride J, Ogorzalek Loo RR, Navazesh M, Wong DT. Differentially expressed protein markers in human submandibular and sublingual secretions.Int J Oncol. 2004 Nov;25(5):1423-30.

Hu S, Yu T, Xie Y, Yang Y, Li Y, Zhou X, Tsung S, Loo RR, Loo JR, Wong DT. Discovery of oral fluid biomarkers for human oral cancer by mass spectrometry. Cancer Genomics Proteomics. 2007 Mar-Apr;4(2):55-64.

Hu S, Xie Y, Ramachandran P, Ogorzalek Loo RR, Li Y, Loo JA, Wong DT. Large-scale identification of proteins in human salivary proteome by liquid chromatography/mass spectrometry and two-dimensional gel electrophoresis-mass spectrometry.Proteomics. 2005 Apr;5(6):1714-28.

Mastali M, Babbitt JT, Li Y, Landaw EM, Gau V, Churchill BM, Haake DA. Optimal probe length and target location for electrochemical detection of selected uropathogens at ambient temperature J Clin Microbiol. 2008 Aug;46(8):2707-16. Epub 2008 Jun 18.

Tan W, Sabet L, Li Y, Yu T, Klokkevold PR, Wong DT, Ho CM. Optical protein sensor for detecting cancer markers in saliva. Biosens Bioelectron. 2008 Oct 15;24(2):266-71. Epub 2008 Apr 6.

Park NJ, Li Y, Yu T, Brinkman BM, Wong DT. Characterization of RNA in saliva.Clin Chem. 2006 Jun;52(6):988-94. Epub 2006 Apr 6.

Yang CY, Brooks E, Li Y, Denny P, Ho CM, Qi F, Shi W, Wolinsky L, Wu B, Wong DT, Montemagno CD Detection of picomolar levels of interleukin-8 in human saliva by SPR..Lab Chip. 2005 Oct;5(10):1017-23. Epub 2005 Aug 18.

Hu S, Denny P, Denny P, Xie Y, Loo JA, Wolinsky LE, Li Y, McBride J, Ogorzalek Loo RR, Navazesh M, Wong DT. Differentially expressed protein markers in human submandibular and sublingual secretions.Int J Oncol. 2004 Nov;25(5):1423-30.

David Elashoff, Myungshin Oh, Nik Brown, Yang Li, David Wong, Steve Horvath. Empirical Study of the Influence of Expression Index on the Standard Statistical Analysis of Oligonucleotide Microarray Data. 2004

Chu-Ya Yang, Evan Brooks,Yang Li, Paul Denny, Chih-Ming Ho, Fengxia Qi, Wenyuan Shi, Lawrence Wolinsky, Benjamin Wu, David T. W. Wong, and Carlo D. Montemagno. Detection of picomolar levels of interleukin-8 in human saliva by SPR. Lab Chip. 2005, 5, 1017–1023.

Mai N. Brooks, Jianghua Wang, Yang Li, Bryan Huang, Myungshin Oh, Sharon Henry, David Elashoff, David Chia, David Wong. Salivary Protein Factors Are Elevated in Breast Cancer Patients. Clin Can Res 2005

Joseph C. Liao, Mitra Mastali, Vincent Gau, Marc A. Suchard, Annette K. Møller, David A. Bruckner, Jane T. Babbitt, Yang Li, Jeffrey Gornbein, Elliot M. Landaw, Edward R. B. McCabe, Bernard M. Churchill, and David A. Haake. Rapid Molecular Identification of Uropathogens in Clinical Urine Specimens Using Electrochemical DNA Biosensors. J Clin Micro 2005

Joseph C. Liao Mitra Mastali, Vincent Gau, Yang Li, Annette Møller, Jane Babbitt, Edward R. B. McCabe, Bernard M. Churchill, David A. Haake. Determinants of signal intensity for bacterial pathogen detection using an electrochemical DNA biosensor array. 2005

Liao JC, Mastali M, Li Y, Gau V, Suchard MA, Babbitt J, Gornbein J, Landaw EM,McCabe ER, Churchill BM, Haake DA. Development of an advanced electrochemical DNA biosensor for bacterial pathogen detection. J Mol Diagn. 2007 Apr;9(2):158-68.

Liao JC, Mastali M, Gau V, Suchard MA, Møller AK, Bruckner DA, Babbitt JT, Li Y, Gornbein J, Landaw EM, McCabe ER, Churchill BM, Haake DA. Use of electrochemical DNA biosensors for rapid molecular identification of ropathogens in clinical urine specimens. J Clin Microbiol. 2006 Feb;44(2):561-70.

An unsteady microfluidic T-form mixer perturbed by hydrodynamic pressure. Ma Y, Sun CP, Fields M, Li Y, Haake DA, Churchill BM, Ho CM. J Micromech Microeng. 2008 Mar 6;18:45015.

Optimal probe length and target location for electrochemical detection of selected uropathogens at ambient temperature. Mastali M, Babbitt JT, Li Y, Landaw EM, Gau V, Churchill BM, Haake DA. J Clin Microbiol. 2008 Aug;46(8):2707-16. Epub 2008 Jun 18.

Rapid antimicrobial susceptibility determination of uropathogens in clinical urine specimens by use of ATP bioluminescence. Ivancic V, Mastali M, Percy N, Gornbein J, Babbitt JT, Li Y, Landaw EM, Bruckner DA, Churchill BM, Haake DA. J Clin Microbiol. 2008 Apr;46(4):1213-9. Epub 2008 Feb 13.

Development of an advanced electrochemical DNA biosensor for bacterial pathogen detection. Liao JC, Mastali M, Li Y, Gau V, Suchard MA, Babbitt J, Gornbein J, Landaw EM, McCabe ER, Churchill BM, Haake DA. J Mol Diagn. 2007 Apr;9(2):158-68.

Use of electrochemical DNA biosensors for rapid molecular identification of uropathogens in clinical urine specimens. Liao JC, Mastali M, Gau V, Suchard MA, Møller AK, Bruckner DA, Babbitt JT, Li Y, Gornbein J, Landaw EM, McCabe ER, Churchill BM, Haake DA. J Clin Microbiol. 2006 Feb;44(2):561-70.

Optical protein sensor for detecting cancer markers in saliva. Tan W, Sabet L, Li Y, Yu T, Klokkevold PR, Wong DT, Ho CM. Biosens Bioelectron. 2008 Oct 15;24(2):266-71. Epub 2008 Apr 6.

Discovery of oral fluid biomarkers for human oral cancer by mass spectrometry. Hu S, Yu T, Xie Y, Yang Y, Li Y, Zhou X, Tsung S, Loo RR, Loo JR, Wong DT. Cancer Genomics Proteomics. 2007 Mar-Apr;4(2):55-64.

Patents:

Two Patents on Clinical Detection of Diseases Using Bodily Fluid and NanoBioSensor

Awards:

UCLA Outstanding Postdoctoral Award Nominee, 2005

Professional Memberships

American Dental Association

Interests

Reading, Watching Movie and Spend time with family.

Dr Rong Zhanfg